Cetrizet D Special Precautions

Cetrizet-D should be used with caution in patients with diabetes, hyperthyroidism, hypertension, tachycardia, arrhythmia, renal or hepatic insufficiency, prostatic hypertrophy or urethral dysfunction, in patients taking alcohol although there is no potentiation of alcohol by cetirizine, and in the elderly.
Cetirizine Hydrochloride: Studies in healthy volunteers at 20 to 25 mg/day have not revealed effects on alertness or reaction time; however, patients are advised not to exceed the recommended dose if driving or operating machinery.
Pseudoephedrine Hydrochloride: Pseudoephedrine should be used with caution in patients taking antihypertensive agents, tricyclic anti-depressants, other sympathomimetic agents such as decongestants, appetite suppressants, amphetamine-like psychostimulants and digitalis. As with other centrally acting stimulants, abuse has been observed for pseudoephedrine. Caution should be exercised in the presence of severe renal or hepatic impairment.
Pseudoephedrine should be used with caution in patients with hypertension, heart disease, diabetes, hyperthyroidism, elevated intraocular pressure and prostatic enlargement. There is no information on the effect of pseudoephedrine on human fertility.
Use in Children: Although cetirizine and pseudoephedrine have both proven to be efficacious in children >2 years, Cetrizet-D has not been tested in children <12 years.
Use in the elderly: Caution is required when administering the drug to patients >50 years.